Photobiologic, toxicologic, and pharmacologic aspects of psoralens.

  • 261 Pages
  • 1.66 MB
  • English

U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute, For sale by the Supt. of Docs., U.S. G.P.O. , Bethesda, Md, Washington, D.C
Psoralens -- Therapeutic use -- Testing -- Congresses., Psoralens -- Toxicology -- Congresses., Psoralens -- Structure-activity relationships -- Congresses., Photochemotherapy -- Congresses., Psoralens -- pharmacodynamics -- congresses., Psoralens -- therapeutic use -- congresses., Psoralens -- toxicology -- congre
SeriesNational Cancer Institute monograph ;, 66, NIH publication ;, no. 84-2692
ContributionsNational Toxicology Program (U.S.), National Cancer Institute (U.S.)
LC ClassificationsRC261 .A448 no. 66, RM666.P88 .A448 no. 66
The Physical Object
Pagination261 p. :
ID Numbers
Open LibraryOL2344994M
LC Control Number86602398

Photobiologic, toxicologic, and pharmacologic aspects of psoralens.

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Proceedings of a conference, Research Triangle Park, North Carolina, March[No authors listed]. Photobiologic, toxicologic, and pharmacologic aspects of psoralens. Bethesda, Md.: United States Department of Health and Human Services, Public And pharmacologic aspects of psoralens.

book Service, National Institutes of Health, National Cancer Institute ; Washington, D.C.: For sale by the Superintendent of Documents, United States Government Printing Office, (OCoLC) Journal: National Cancer Institute monograph[/12] Photobiologic, toxicologic, and pharmacologic aspects of psoralens.

Proceedings of a conference, Toxicologic Triangle. Get this from a library. Photobiologic, toxicologic, and pharmacologic aspects of psoralens: proceedings of a conference held at Research Triangle Park, North Carolina, March[Madhu A Pathak; June K Dunnick; National Toxicology Program (U.S.);].

Author(s): Pathak,Madhu A; Dunnick,June K; National Toxicology Program (U.S.) Title(s): Photobiologic, toxicologic, and pharmacologic aspects of psoralens: proceedings of a conference held at Research Triangle Park, North Carolina, March/ sponsored by the National Toxicology Program, National Institute of Environmental Health Sciences ; scientific editors, Madhu A.


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An exchange hydrogenation reaction on trioxsalen yields two isomeric dihydro analogues for which a combined HPLC-supercritical fluid chromatography me. PHOTOBIOLOGIC, TOXICOLOGIC AND PHARMACOLOGIC ASPECTS OF PSORALENS by toxicology) and a great selection of related books, art and collectibles available now at The roots of psoralen therapy for vitiligo can be traced as far back as 1, B.C.

in Atharva Veda in which the early Ayurvedic therapy practiced by ancient Hindu priests is described. Extracts of Bavachee seeds or And pharmacologic aspects of psoralens. book Corylifolia and other plants containing psoralens were used in folk remedies by people of various cultures of India.

Even. Wolff K, Honigsmann H () Safety and therapeutic effectiveness of selected psoralens in psoriasis. In: Greenwald P (ed) Photobiologic, toxicologic, and pharmacologic aspects of psoralens.

(National Cancer Institute Monograph 66) U.S. Government Printing Office, Washington, D.C. Studies on P content and mixed-function oxidase and epoxide hydrolase activity Mol Pharmacol () Pathak, M.A.

Dunnick, J.K. Photobiologic, Toxicologic, and Pharmacologic Aspects of Psoralens Monograph No. 66 () Public Health Service, National Cancer Institute US Department of Health and Human Services Social Aspects of Drug Discovery, Development and Commercialization provides an insightful analysis of the drug discovery and development landscape as it relates to society.

This book examines the scientific, legal, philosophical, economic, political, ethical and cultural factors that contribute to drug development. National Cancer Institute Monogr December Photobiologic, Toxicologic, and Pharmacologic Aspects of Psoralens (NIH Publication No.

We have examined DNA repair in the dihydrofolate reductase (DHFR) gene in cultured human cells treated with 4′-hydroxymethyl-4,5′,8-trimethylpsoralen (HMT) using a newly developed assay for interstrand DNA cross-linking in defined genomic sequences.

Within 24 hr, 80% of the cross-links, but only 45% of the monoadducts, were removed from a 32 kb transcribed sequence, demonstrating that. 5-Methoxymethyl-2H-benzofuro[3,2-g]benzopyranone was synthesized and its crystal structure was determined and compared with the optimal conformation arrived at by MM and AM1 theoretical calculations.

The latter indicated that the tetracyclic skeleton is planar with total length (C2–C8) å, and that the line joining the conters of the terminal-benzene and furan rings makes an.

CiteScore: ℹ CiteScore: CiteScore measures the average citations received per peer-reviewed document published in this title. CiteScore values are based on citation counts in a range of four years (e.g.

) to peer-reviewed documents (articles, reviews, conference papers, data papers and book chapters) published in the same four calendar years, divided by the number of. Psoralen-induced skin photosensitization and the therapeutic action of psoralens involve two distinct types of reactions, and these two reactions occur independently of each other and concurrently when the psoralen-treated skin (oral or topical) is exposed to to nm of radiation.

Regulatory Toxicology and Pharmacology publishes peer reviewed articles that involve the generation, evaluation, and interpretation of experimental animal and human data that are of direct importance and relevance for regulatory aspects with respect to toxicological and pharmacological regulations in.

The Toxicologic Assessment of Pharmaceutical and Biotechnology Products The World Health Organization (WHO) Scientific Group has defined a drug as “any substance or product that is used or intended to be used to modify or explore physiological systems or pathological states for the benefit of the recipient” [].

Toxicology, study of poisons and their effects, particularly on living systems. Because many substances are known to be poisonous to life (whether plant, animal, or microbial), toxicology is a broad field, overlapping with biochemistry, histology, pharmacology, pathology, and many other disciplines.

Description Photobiologic, toxicologic, and pharmacologic aspects of psoralens. PDF

G Rodighiero's research works with 2, citations and reads, including: Monofunctional 4′,5′-photocy-cloadduct between ′-dimethylangelicin and thymine.

What is pharmacology. Pharmacology is the branch of science concerned with the study of drugs and how they affect living organisms. When most people think about the word “drug”, they usually associate it with illegal substances, such as cannabis, heroin or cocaine.

But in pharmacology, the word “drug” has a much broader meaning than that. Morison WL. In vivo effects of psoralens plus longwave ultraviolet radiation on immunity. In: Photobiologic, Toxicologic, and Pharmacologic Aspects of Psoralens.

Bethesda, Md: National Institutes of Health; (December) National Cancer Institute Monograph Scope. Photochemical & Photobiological Sciences (PPS) is a monthly journal for the publication of original research papers (Full papers), Perspectives, Communications and Technical notes of current interest in the areas of photochemistry and photobiology.

The journal also contains a Forum section. PPS is published by the Royal Society of Chemistry and is the official journal of the European. A pharmacologic response results when the drug concentration at the site of action reaches or exceeds the minimum effective concentration (MEC).

The suggested dosing regimen, including starting dose, maintenance dose, dosage form, and dosing interval, is determined in clinical trials to provide the drug concentrations that are therapeutically.

Dalziel, JM "The Useful Plants in West Africa," Crown Agents, London, SOURCE BOOKS AND MAJOR REVIEWS FOR SECTION 1 Pathak, M A, and Dunnick, J K (eds) "Photobiologic, Toxicologic, and Pharmacologic Aspects of Psoralens," Nat Cancer Inst Monograph No 66, NIH publ NoU S Department of Health and Human Services.

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Article. 8-Methoxypsoralen suppresses production of ovarian aromatase proteins. October ; Toxin Reviews 24(2) Author: Michaelbrent Collings Publisher: Michaelbrent Collings ISBN: Size: MB Format: PDF, Kindle View: Get Books. Darkbound Darkbound by Michaelbrent Collings, Darkbound Books available in PDF, EPUB, Mobi Format.

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The Pharmacology Education Project (PEP) is being developed by The International Union of Basic and Clinical Pharmacology (IUPHAR), with support from sponsors, as a service to the international pharmacology community.

Drupal site built by The University of Edinburgh. BMC Pharmacology and Toxicology is an open access, peer-reviewed journal that considers articles on all aspects of chemically defined therapeutic and toxic agents. The journal welcomes submissions from all fields of experimental and clinical pharmacology including clinical trials and toxicology.As nouns the difference between pharmacology and toxicology is that pharmacology is (medicine) the science that studies the effects of chemical compounds on living animals, especially the science of the manufacture, use and effects of medicinal drugs while toxicology is (sciences|pharmacology) the branch of pharmacology that deals with the nature, effect, detection and treatment of poisons and.Toxicology and Applied Pharmacology Impact Factor, IF, number of article, detailed information and journal factor.